Rekombinanter CBX4 Antikörper
Kurzübersicht für Rekombinanter CBX4 Antikörper (ABIN7828111)
Target
Alle CBX4 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Recombinant CBX4 Monoclonal Antibody
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Aufreinigung
- Protein A purified
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Immunogen
- Recombinant human CBX4 fragment
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Isotyp
- IgG, kappa
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Applikationshinweise
- WB(human) 1:500-1:1000,WB(rat) 1:1000-1:5000,IHC 1:200-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Haltbarkeit
- 12 months
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- CBX4 (Chromobox Homolog 4 (CBX4))
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Andere Bezeichnung
- CBX4
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Hintergrund
- Cbx,CBX4,CBX4 is a component of the PRC1 complex, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. CBX4 itself is a SUMO E3 ligase, and its function influences EMT, DNA damage response, tumor angiogenesis, and self-renewal. E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. It is involved in the SUMOylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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Molekulargewicht
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Calculated MW: 61 kDa
Observed MW: 61 kDa
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UniProt
- O00257
Target
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