Rekombinanter BRD2 Antikörper (pSer37)

Produktnummer ABIN7828050

Der Kaninchen Monoklonal anti-BRD2 Antikörper (Klon A809) (ABIN7828050) detektiert spezifisch BRD2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter BRD2 Antikörper (pSer37) (ABIN7828050)

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser BRD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: A809

Produktdetails anti-BRD2 Antikörper

Bindungsspezifität: pSer37

Verwendungszweck: Recombinant Phospho-BRD2 (S37) Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human BRD2 (phospho S37) fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:4000-1:20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu BRD2

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Andere Bezeichnung: BRD2

Hintergrund: RNF,BRD,FSRG,RING,KIAA,BRD2-IT,BRD2,BRD2-IT1,D6S113E,FSH,FSRG1,NAT,O27.1.1,RING3,RNF3,KIAA9001,Brd2 is a highly conserved member of the BET subfamily of bromodomain proteins that contain two tandem N-terminal bromodomains and a single C-terminal extra-terminal (ET) domain. In addition to its involvement in guiding the expression of cell cycle genes through its binding to multiple E2Fs, Brd2 has been shown to be associated with several regulators of transcription, including TFIID and Swi/Snf complexes. First identified as a nuclear serine/threonine kinase, Brd2, like other bromodomain proteins, is thought to function in mammalian development by regulating chromatin structure and transcription. Brd2 has been shown to bind to histone H4 via acetylated Lys12, a substrate of several histone acetyltransferase transcriptional coactivators. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 88 kDa

Observed MW: 110 kDa The actual band is not consistent with the expectation.

UniProt: P25440

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion