Rekombinanter ATG9A Antikörper

Produktnummer ABIN7828028

Der Kaninchen Monoklonal anti-ATG9A Antikörper wird verwendet zum Nachweis von ATG9A in Proben von Human. Er wurde validiert für WB, IHC, IF und FACS.

Kurzübersicht für Rekombinanter ATG9A Antikörper (ABIN7828028)

Target: ATG9A (ATG9 Autophagy Related 9 Homolog A (S. Cerevisiae) (ATG9A))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ATG9A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: A507

Produktdetails anti-ATG9A Antikörper

Verwendungszweck: Recombinant ATG9A Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human ATG9A fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50,FCM 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu ATG9A

Target: ATG9A (ATG9 Autophagy Related 9 Homolog A (S. Cerevisiae) (ATG9A))

Andere Bezeichnung: ATG9A

Hintergrund: MGD,mATG,APG9L,ATG9A,APG9L1,MGD3208,mATG9,APG9 autophagy 9-like 1,APG9 like 1,APG9-like 1,ATG9,ATG9 autophagy related 9 homolog A,ATG9 autophagy related 9 homolog A (S. cerevisiae),Autophagy 9-like 1 protein,Autophagy related 9A,Autophagy related protein 9A,Autophagy-related protein 9A,OTTHUMP00000206046,OTTHUMP00000206048,OTTHUMP00000206049,OTTHUMP00000206062,ATG9A are lipid scramblases that play a role in autophagosome expansion. ATG9A is present in numerous intracellular compartments, including the trans-Golgi network and early and recycling endosomes, and traffics through the secretory pathway to the plasma membrane and to the endocytic pathway from the plasma membrane. ATG9A protects cells against plasma membrane damage caused by a spectrum of exogenous and endogenous agents, including permeabilization by gasdermin and mixed lineage kinase domain like (MLKL), which generate pores at the plasma membrane or perturb plasma membrane integrity, respectively, during programmed cell death processes of pyroptosis and necroptosis. We furthermore define the ATG9A-IQGAP1 apparatus that integrates with the ESCRT system to cooperatively heal areas of plasma membrane damage. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 94 kDa

Observed MW: 100 kDa The actual band is not consistent with the expectation.

UniProt: Q7Z3C6