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GPC1 Antikörper (AA 301-400) (Biotin)

This anti-GPC1 antibody (ABIN740102) is a Rabbit Polyclonal antibody detecting GPC1 in ELISA, IHC (p), IHC (fro). Suitable for Human.
Produktnummer ABIN740102

Kurzübersicht für GPC1 Antikörper (AA 301-400) (Biotin) (ABIN740102)

Target

Alle GPC1 Antikörper anzeigen
GPC1 (Glypican 1 (GPC1))

Reaktivität

  • 58
  • 18
  • 16
Human

Wirt

  • 71
  • 10
  • 2
  • 1
Kaninchen

Klonalität

  • 71
  • 11
  • 1
Polyklonal

Konjugat

  • 32
  • 12
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GPC1 Antikörper ist konjugiert mit Biotin

Applikation

  • 39
  • 26
  • 26
  • 24
  • 22
  • 17
  • 9
  • 9
  • 7
  • 7
  • 5
  • 4
  • 2
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 15
    • 14
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-400

    Homologie

    Human,Mouse,Rat,Dog,Cow,Horse

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human glypican 1

    Isotyp

    IgG
  • Applikationshinweise

    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    GPC1 (Glypican 1 (GPC1))

    Andere Bezeichnung

    Glypican 1

    Hintergrund

    Synonyms: glypican, Glypican-1, GPC1

    Background: Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.

    Gen-ID

    2817

    UniProt

    P35052

    Pathways

    Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation
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