Der Kaninchen-Polyklonal Anti-DGCR8-Antikörper wurde für IF und IHC validiert. Er ist geeignet zum Nachweis von DGCR8 in Proben aus Zebrafisch (Danio rerio).
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Target
DGCR8
(DiGeorge Syndrome Critical Region Gene 8 (DGCR8))
Andere Bezeichnung
DGCR8
Hintergrund
The DGCR8 microprocessor complex subunit (DiGeorge syndrome chromosomal [or critical] region 8) is a protein that in humans is encoded by the DGCR8 gene. This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.