KLRC2 Antikörper

Produktnummer ABIN739950

Dieses Anti-KLRC2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KLRC2 in ELISA, FACS, IHC (p), IF (cc), IF (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für KLRC2 Antikörper (ABIN739950)

Target: KLRC2 (Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLRC2 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-KLRC2 Antikörper

Kreuzreaktivität: Affe

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NKG2C

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu KLRC2

Target: KLRC2 (Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2))

Andere Bezeichnung: NKG2C

Hintergrund:

Synonyms: KLRC1, NKG2-A/NKG2-B type II integral membrane protein, CD159a, NKG2-A/B-activating NK receptor, NK cell receptor A, NKG2A, NKG2B, KLRC2, NKG2-C type II integral membrane protein, CD159c, NK cell receptor C, NKG2-C-activating NK receptor, NKG2C, KLRC3, NKG2-E type II integral membrane protein, NK cell receptor E, NKG2-E-activating NK receptor, NKG2E, KLRC4, NKG2-F type II integral membrane protein, NK cell receptor F, NKG2-F-activating NK receptor, NKG2F.

Background: Natural killer (NK) cells are lymphocytes that can mediate the lysis of certain tumor cells and virus infected cells without being previously activated. They can also regulate specific humoral and cell mediated immunity. NK cells preferentially express several calcium dependent (C type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C type lectin genes preferentially expressed on NK cells.

Molekulargewicht: 25kDa

Gen-ID: 3822

UniProt: P26717