ASCL1 Antikörper (AA 151-236) (Cy5)

Produktnummer ABIN738475

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ASCL1 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für ASCL1 Antikörper (AA 151-236) (Cy5) (ABIN738475)

Target: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASCL1 Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ASCL1 Antikörper (Cy5)

Bindungsspezifität: AA 151-236

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ASCL1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ASCL1

Target: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Andere Bezeichnung: ASCL1

Hintergrund:

Synonyms: ASH1, HASH1, MASH1, bHLHa46, Achaete-scute homolog 1, ASH-1, Class A basic helix-loop-helix protein 46, ASCL1

Background: Transcription factor that controls transcriptional expression of its target genes by binding to the E box (5'-CANNTG-3'). Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Essential for the generation of olfactory and autonomic neurons (By similarity).

Gen-ID: 429

UniProt: P50553

Pathways: Dopaminergic Neurogenesis