Rekombinanter FOXM1 Antikörper (AA 650-700)
Kurzübersicht für Rekombinanter FOXM1 Antikörper (AA 650-700) (ABIN7795806)
Target
Alle FOXM1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 650-700
-
Verwendungszweck
- Rabbit anti-FOXM1 Recombinant Monoclonal Antibody [BLR365N]
-
Aufreinigung
- Purified
-
Immunogen
- between 650 and 700
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB,11,000,ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,6 μL/mg lysate
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1000 μg/mL
-
Buffer
- Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Informationen zur Lagerung
- 2 - 8 °C
-
Haltbarkeit
- 12 months
-
-
- FOXM1 (Forkhead Box M1 (FOXM1))
-
Andere Bezeichnung
- FOXM1
-
Hintergrund
- FOXM1 belongs to a large family of Forkhead transcription factors that possesses a winged-helix DNA-binding domain called Forkhead box (FOX). It is a transcription factor critical to cell cycle progression via its role in coordinating the G2/M phase transition. FOXM1 is ubiquitously expressed in proliferating cells but is absent in differentiated cells. FOXM1 overexpression has been detected in a variety of tumor types including breast, lung, prostate, and liver cancer, and appears to be involved in tumorigenesis-associated processes such as angiogenesis and metastasis. In light of these findings, FOXM1 has recently become an attractive target for anti-cancer therapy.
-
Gen-ID
- 2305
-
UniProt
- Q08050
-
Pathways
- Positive Regulation of Response to DNA Damage Stimulus
Target
-