Rekombinanter CX3CR1 Antikörper (AA 300-350)

Produktnummer ABIN7795801

Der Kaninchen Monoklonal anti-CX3CR1 Antikörper (Klon BLR362N) (ABIN7795801) detektiert spezifisch CX3CR1 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter CX3CR1 Antikörper (AA 300-350) (ABIN7795801)

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CX3CR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: BLR362N

Produktdetails anti-CX3CR1 Antikörper

Bindungsspezifität: AA 300-350

Verwendungszweck: Rabbit anti-CX3CR1 Recombinant Monoclonal Antibody [BLR362N]

Aufreinigung: Purified

Immunogen: between 300 and 350

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 500 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2 - 8 °C

Haltbarkeit: 12 months

Details zu CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Andere Bezeichnung: CX3CR1

Hintergrund: CX3CR1 is a receptor for the C-X3-C chemokine fractalkine (CX3CL1) which is present on many early leukocyte cells. Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis. CX3CR1 is also a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. [taken from NCBI Entrez Gene (Gene ID: 1524)].

Gen-ID: 1524

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin