Der Kaninchen Monoklonal anti-RUNX2 Antikörper (Klon BLR360N) (ABIN7795798) detektiert spezifisch RUNX2 in WB, IHC, IP und ICC.
Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.
RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with a Runt DNA-binding domain. RUNX2 is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. RUNX2 can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. [provided by RefSeq, Jul 2016] [taken from NCBI Entrez Gene (Gene ID: 860)].