Rekombinanter NF-KappaB2 (/p52) (AA 1-50) Antikörper

Produktnummer ABIN7795782

Der Kaninchen Monoklonal anti-NF-KappaB2 (/p52) Antikörper wird verwendet zum Nachweis von NF-KappaB2 (/p52) in Proben von Human. Er wurde validiert für FACS, ICC, IHC, IP und WB.

Kurzübersicht für Rekombinanter NF-KappaB2 (/p52) (AA 1-50) Antikörper (ABIN7795782)

Target: NF-KappaB2 (/p52)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Applikation: Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)

Klon: BLR350N

Produktdetails

Bindungsspezifität: AA 1-50

Verwendungszweck: Rabbit anti-NF-kappaB2 (p100/p52) Recombinant Monoclonal Antibody [BLR350N]

Aufreinigung: Purified

Immunogen: between 1 and 50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,11000,ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,6 μL/mg lysate,Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 1 μL per 1 x 10^6 cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2 - 8 °C

Haltbarkeit: 12 months

Antigendetails

Target: NF-KappaB2 (/p52)

Hintergrund: The NFKB2 gene encodes a 100 kDa protein that can undergo co-translational processing to also yield a 52 kDa protein. The 52 kDa protein is also known as NF-kappa B2/p52 and is one of five monomeric subunits that are part of the Rel family of proteins that dimerize to form the NF-kappa B (nuclear factor that binds the kappa immunoglobulin light chain gene enhancer) transcription factor. Members of the Rel family of proteins include NF-kappa B1/p50, NF-kappa B2/p52, RelA/p65, c-Rel, and RelB. The 100 kDa product is also known as p100 or I kappa B delta. P100/I kappa B delta has been shown to function as an inhibitor protein that interacts with NF-kappa B and inhibit its DNA binding activity. P100/I kappa B delta is a member of the I kappa B family of proteins which includes I kappa B-beta, I kappa B-delta/NF-kappa B2/p100, I kappa B-gamma/NF-kappa B1/p105, I kappa B-epsilon, I kappa B-zeta, and Bcl3. The classical description of the NF-kappa B transcription factor is a transcription factor that reprograms gene expression of the immune system in response to injury, infection, and stress.

Gen-ID: 4791

UniProt: Q00653