Rekombinanter PRDM1 Antikörper (AA 375-425)
Kurzübersicht für Rekombinanter PRDM1 Antikörper (AA 375-425) (ABIN7795637)
Target
Alle PRDM1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 375-425
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Verwendungszweck
- Rabbit anti-PRDM1/Blimp-1 Recombinant Monoclonal Antibody [BLR247L]
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Aufreinigung
- Purified
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Immunogen
- Between 375 and 425
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Isotyp
- IgG
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Applikationshinweise
- WB,11000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1000 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2 - 8 °C
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Haltbarkeit
- 12 months
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- PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
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Andere Bezeichnung
- PRDM1/BLIMP-1
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Hintergrund
- PDRM1, aka Blimp-1, is a transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. PDRM1 binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter and acts as a repressor of beta-interferon gene expression. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75626].
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Gen-ID
- 639
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UniProt
- O75626
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Pathways
- Regulation of Muscle Cell Differentiation
Target
-