TS (C-Term) Antikörper
Kurzübersicht für TS (C-Term) Antikörper (ABIN7795593)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Rabbit anti-TS Antibody Affinity Purified
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Homologie
- Bovine,Dog,Monkey,Pig,Rabbit,Rat
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Between 263 and C-terminus
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Isotyp
- IgG
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Applikationshinweise
- IHC,1500 - 12000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,6 μg/mg lysate,WB,12000 - 110,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2 - 8 °C
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Haltbarkeit
- 12 months
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- TS
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Hintergrund
- Thymidylate synthetase (TS) catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. TS is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs [taken from NCBI Entrez Gene (Gene ID: 7298)].
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Gen-ID
- 7298
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UniProt
- P04818
Target
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