Rekombinanter CD370 & CD47 Antikörper

Produktnummer ABIN7795543

Der Maus Bispecific anti-CD370 & CD47 Antikörper (Klon 10B4-A4) (ABIN7795543) detektiert spezifisch CD370 & CD47 in ELISA, FACS, ICC, IHC, in vivo und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für Rekombinanter CD370 & CD47 Antikörper (ABIN7795543)

Target: CD370 & CD47

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus

Wirt: Maus

Klonalität: Bispecific

Applikation: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), In vivo Studies (in vivo), Western Blotting (WB)

Güteklasse: In vivo Grade

Klon: 10B4-A4

Produktdetails

Expressionssystem: Mammalian cells

Verwendungszweck: In Vivo Grade Recombinant Anti-mouse CD370 / CD47 Bispecific Antibody, Mouse IgG2c LALAPG Kappa (Clone 10B4 / A4)

Produktmerkmale: The rat anti-mouse CD370 (Clec9A or DNGR-1) monoclonal antibody 10B4 (rat IgG2a kappa) reacts with the mouse CD370 protein. CLEC9A (C-type lectin domain family 9 member A), a transmembrane glycoprotein with a single extracellular C-type lectin domain (CTLD), plays a role in the immune response. As an activation receptor, CLEC9A is expressed on myeloid lineage cells, helps process material from dead cells, recognizes filamentous actin when cell membranes are damaged, and helps present antigens to cytotoxic T cells. CLEC9A has an intracellular cytoplasmic tail with potential signaling motifs. CLEC9A is expressed on a subset of BDCA3+ dendritic cells and CD16- monocytes in humans, and is expressed on CD8+ conventional DCs and plasmacytoid DCs in mice. It is under investigation how the recombinant anti-mouse CD370 / CD47 bispecific antibodies (10B4 / A4) behave different from the individual monoclonal antibodies and their combination. Our recombinant anti-mouse CD370 / CD47 bispecific antibodies have a part (variable regions) or complete amino acid sequences of the rat anti-mouse CD370 antibody (hybridoma clone name or number: 10B4) and the rat anti-mouse CD47 antibody (hybridoma clone name or number: A4).

Aufreinigung: Protein A or G affinity column

Reinheit: >95 % by reducing SDS-PAGE

Endotoxin-Niveau: < 1 EU per 1 mg of the protein by the LAL method

Isotyp: IgG2c, L234A, L235A, P329G, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: > 3 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Antigendetails

Target: CD370 & CD47

Sub Type: Bispecific