Rekombinanter CD276 (Ifinatamab Biosimilar) Antikörper

Produktnummer ABIN7795144

Der Humanized Monoklonal anti-CD276 (Ifinatamab Biosimilar) Antikörper (ABIN7795144) detektiert spezifisch CD276 (Ifinatamab Biosimilar) in FACS und in vivo. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter CD276 (Ifinatamab Biosimilar) Antikörper (ABIN7795144)

Target: CD276 (Ifinatamab Biosimilar)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Humanized

Klonalität: Monoklonal

Konjugat: Dieser CD276 (Ifinatamab Biosimilar) Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), In vivo Studies (in vivo)

Güteklasse: Research Grade

Produktdetails anti-CD276 (Ifinatamab Biosimilar) Antikörper

Expressionssystem: Mammalian cells

Verwendungszweck: Ifinatamab Biosimilar, Human B7-H3 Monoclonal Antibody

Produktmerkmale: What is ifinatamab biosimilar research grade? Ifinatamab is a humanized IgG1-kappa monoclonal antibody against the human B7-H3 (CD276) protein, a type I transmembrane protein belonging to the B7 family which includes immune checkpoint molecules CTLA-4 and PD-L1. B7-H3 is highly expressed in various types of solid tumors with low expression in normal (healthy) tissues. It was reported that B7-H3 overexpression is associated with poor prognosis in several types of cancers. Ifinatamab biosimilar uses the same protein sequences as the therapeutic antibody ifinatamab.

Aufreinigung: Protein A or G affinity column

Reinheit: >95 % by reducing SDS-PAGE

Endotoxin-Niveau: < 1 EU per 1 mg of the protein by the LAL method

Immunogen: Human B7-H3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: > 3 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Details zu CD276 (Ifinatamab Biosimilar)

Target: CD276 (Ifinatamab Biosimilar)

Andere Bezeichnung: Ifinatamab Biosimilar

Substanzklasse: Biosimilar