Rekombinanter PCSK9 (Evolocumab Biosimilar) Antikörper

Produktnummer ABIN7795143

Der Maus Monoklonal Anti-PCSK9 (Evolocumab Biosimilar) Antikörper wurde für FACS und in vivo validiert. Er ist geeignet, PCSK9 (Evolocumab Biosimilar) in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter PCSK9 (Evolocumab Biosimilar) Antikörper (ABIN7795143)

Target: PCSK9 (Evolocumab Biosimilar)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PCSK9 (Evolocumab Biosimilar) Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), In vivo Studies (in vivo)

Güteklasse: Research Grade

Produktdetails anti-PCSK9 (Evolocumab Biosimilar) Antikörper

Expressionssystem: Mammalian cells

Verwendungszweck: Evolocumab Biosimilar, Human PCSK9 Monoclonal Antibody

Produktmerkmale: What is evolocumab biosimilar research grade? Evolocumab (trade name Repatha) is a fully human monoclonal antibody that inhibits proprotein convertase subtilisin-kexin type 9 (PCSK9) and lowers low-density lipoprotein (LDL) cholesterol levels by approximately 60 % . The PCSK9 protein targets LDL receptors for degradation. Evolocumab binds to the circulating PCSK9 protein, inhibiting it from binding to the LDLR, in turn preventing PCSK9-mediated LDLR degradation and permitting the LDLR to recycle back to the liver cell surface. By inhibiting the binding of PCSK9 to LDLR, evolocumab increases the number of LDLRs available to clear LDL from the blood, thereby lowering LDL-C levels. Evolocumab biosimilar uses the same protein sequences as the therapeutic antibody evolocumab.

Aufreinigung: Protein A or G affinity column

Reinheit: >95 % by reducing SDS-PAGE

Endotoxin-Niveau: < 1 EU per 1 mg of the protein by the LAL method

Immunogen: Human PCSK9

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: > 3 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Details zu PCSK9 (Evolocumab Biosimilar)

Target: PCSK9 (Evolocumab Biosimilar)

Andere Bezeichnung: Evolocumab Biosimilar

Substanzklasse: Biosimilar