Rekombinanter IL-4RA (Dupilumab Biosimilar) Antikörper

Produktnummer ABIN7795142

Dieser Maus Monoklonal Antikörper erkennt spezifisch IL-4RA (Dupilumab Biosimilar) in FACS und in vivo. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter IL-4RA (Dupilumab Biosimilar) Antikörper (ABIN7795142)

Target: IL-4RA (Dupilumab Biosimilar)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-4RA (Dupilumab Biosimilar) Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), In vivo Studies (in vivo)

Güteklasse: Research Grade

Produktdetails anti-IL-4RA (Dupilumab Biosimilar) Antikörper

Expressionssystem: Mammalian cells

Verwendungszweck: Dupilumab Biosimilar, Endotoxin 0.05 EU/mg

Produktmerkmale: What is dupilumab biosimilar research grade? Dupilumab is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis. It is also used for the treatment of eosinophilic esophagitis and prurigo nodularis. Dupilumab binds to the alpha subunit of the interleukin-4 receptor (IL-4Ra), making it a receptor antagonist. Through blockade of IL-4Ra, dupilumab modulates signaling of both the interleukin 4 and interleukin 13 pathways. Dupilumab biosimilar uses the same protein sequences as the therapeutic antibody dupilumab.

Aufreinigung: Protein A or G affinity column

Reinheit: >95 % by reducing SDS-PAGE

Endotoxin-Niveau: Less than 0.5 EU/mg of protein as determined by LAL method

Immunogen: Human IL4R alpha

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: > 3 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Details zu IL-4RA (Dupilumab Biosimilar)

Target: IL-4RA (Dupilumab Biosimilar)

Andere Bezeichnung: Dupilumab Biosimilar

Substanzklasse: Biosimilar