Dieser Maus Monoklonal Antikörper detektiert spezifisch VEGFA (Brolucizumab Biosimilar) in FACS und in vivo. Es zeigt Reaktivität gegenüber Proben von Human.
Brolucizumab Biosimilar uses the same protein sequences as the therapeutic antibody brolucizumab. Brolucizumab is a monoclonal antibody indicated to treat neovascular age related macular degeneration. Brolucizumab is a vascular endothelial growth factor (VEGF) inhibitor which targets the major VEGF-A isoforms: VEGF110, VEGF121, and VEGF165. Inhibition of these VEGF-A isoforms reduce proliferation of endothelial cells, vascularization of the tissue, and permeability of the vasculature.
Aufreinigung
Protein A or G affinity column
Reinheit
>95 % by reducing SDS-PAGE
Endotoxin-Niveau
< 1 EU per 1 mg of the protein by the LAL method
Immunogen
Human VEGF-A
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
> 3 mg/mL
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.