Rekombinanter CD38 (Isatuximab Biosimilar) Antikörper
Kurzübersicht für Rekombinanter CD38 (Isatuximab Biosimilar) Antikörper (ABIN7795129)
Target
Antikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Expressionssystem
- Mammalian cells
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Verwendungszweck
- Isatuximab Biosimilar, CD38 Monoclonal Antibody
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Produktmerkmale
- Isatuximab Biosimilar uses the same protein sequences as the therapeutic antibody isatuximab. Isatuximab is a humanized, IgG1-derived monoclonal antibody (mAb) produced from a Chinese hamster ovary (CHO) cell line. Structurally, isatuximab is comprised of two identical immunoglobulin kappa light chains and two identical immunoglobulin gamma heavy chains. It is a cytolytic antibody targeted against CD38, a glycoprotein found on the surface of some immune cells that is highly expressed by malignant plasma cells in multiple myeloma. Along with daratumumab, another anti-CD38 monoclonal antibody, isatuximab constitutes a novel treatment modality for patients with difficult-to-treat multiple myeloma.
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Aufreinigung
- Protein A or G affinity column
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Reinheit
- >95 % by reducing SDS-PAGE
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Endotoxin-Niveau
- < 1 EU per 1 mg of the protein by the LAL method
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Immunogen
- Human CD38
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- > 3 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- CD38 (Isatuximab Biosimilar)
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Andere Bezeichnung
- Isatuximab Biosimilar
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Substanzklasse
- Biosimilar
Target
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