Rekombinanter MS4A1 (Obinutuzumab Biosimilar) Antikörper
Kurzübersicht für Rekombinanter MS4A1 (Obinutuzumab Biosimilar) Antikörper (ABIN7795118)
Target
Antikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Expressionssystem
- Mammalian cells
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Verwendungszweck
- Obinutuzumab Biosimilar, CD20 Monoclonal Antibody
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Produktmerkmale
- Obinutuzumab Biosimilar uses the same protein sequences as the therapeutic antibody obinutuzumab. Obinutuzumab is an antineoplastic CD20 antibody used to treat untreated chronic lymphocytic leukemia in combination with chlorambucil. In contrast to rituximab, which is a classic type I CD20 antibody, obinutuzumab binds to type II CD20 antibodies. This allows obinutuzumab to have a much higher induction of antibody-dependant cytotoxicity and a higher direct cytotoxic effect than the classic CD20 antibodies.
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Aufreinigung
- Protein A or G affinity column
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Reinheit
- >95 % by reducing SDS-PAGE
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Endotoxin-Niveau
- < 1 EU per 1 mg of the protein by the LAL method
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Immunogen
- Human CD20
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- > 3 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- MS4A1 (Obinutuzumab Biosimilar)
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Andere Bezeichnung
- Obinutuzumab Biosimilar
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Substanzklasse
- Biosimilar
Target
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