Rekombinanter CD80 (Galiximab Biosimilar) Antikörper

Produktnummer ABIN7795110

Der Humanized Monoklonal Anti-CD80 (Galiximab Biosimilar) Antikörper wurde für FACS und in vivo validiert. Er ist geeignet, CD80 (Galiximab Biosimilar) in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter CD80 (Galiximab Biosimilar) Antikörper (ABIN7795110)

Target: CD80 (Galiximab Biosimilar)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Humanized

Klonalität: Monoklonal

Konjugat: Dieser CD80 (Galiximab Biosimilar) Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), In vivo Studies (in vivo)

Güteklasse: Research Grade

Produktdetails anti-CD80 (Galiximab Biosimilar) Antikörper

Expressionssystem: Mammalian cells

Verwendungszweck: Galiximab Biosimilar, CD80 Monoclonal Antibody

Produktmerkmale: A humanized IgG1 monoclonal antibody directed against CD80, the natural ligand for the T-cell antigen CD28 which mediates T-cell and B-cell adhesion. Galiximab binds to CD80 expressed on the cell surfaces of follicular lymphomas, resulting in antibody-dependent cell-mediated cytotoxicity (ADCC). CD80 is expressed on activated B-cells and gamma-interferon-stimulated monocytes and is often expressed at low levels on the surfaces of follicular lymphoma cells and other lymphoid malignancies. Galiximab, an IgG(1) anti-CD80 antibody, binds to CD80, a costimulatory molecule involved in T-cell activation. Reduction in lesional, activated T cells induces improvement in psoriatic plaques.

Aufreinigung: Protein A or G affinity column

Reinheit: >95 % by reducing SDS-PAGE

Endotoxin-Niveau: < 1 EU per 1 mg of the protein by the LAL method

Immunogen: Human CD80

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: > 3 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Details zu CD80 (Galiximab Biosimilar)

Target: CD80 (Galiximab Biosimilar)

Andere Bezeichnung: Galiximab Biosimilar

Substanzklasse: Biosimilar