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Rekombinanter CD22 (Epratuzumab Biosimilar) Antikörper

Dieser Anti-CD22 (Epratuzumab Biosimilar) Antikörper ist ein Humanized Monoklonal Antikörper zur Detektion von CD22 (Epratuzumab Biosimilar) in FACS und in vivo. Geeignet für Human.
Produktnummer ABIN7795108

Kurzübersicht für Rekombinanter CD22 (Epratuzumab Biosimilar) Antikörper (ABIN7795108)

Target

CD22 (Epratuzumab Biosimilar)

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 4
  • 2
  • 2
Human

Wirt

  • 2
  • 1
  • 1
Humanized

Klonalität

  • 2
  • 2
Monoklonal

Konjugat

  • 4
Dieser CD22 (Epratuzumab Biosimilar) Antikörper ist unkonjugiert

Applikation

  • 3
  • 2
  • 2
  • 1
Flow Cytometry (FACS), In vivo Studies (in vivo)

Güteklasse

Research Grade
  • Expressionssystem

    Mammalian cells

    Verwendungszweck

    Epratuzumab Biosimilar, Endotoxin 0.05 EU/mg

    Produktmerkmale

    Epratuzumab Biosimilar uses the same protein sequences as the therapeutic antibody epratuzumab. Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). This agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus. Epratuzumab is a recombinant, humanized monoclonal antibody directed against CD22, a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells. It binds with high specificity to normal B-cells and B-cell tumors at the third Ig-like domain of CD22. After binding to CD22, epratuzumab's predominant antitumor activity appears to be mediated through antibody-dependent cellular cytotoxicity (ADCC).

    Aufreinigung

    Protein A or G affinity column

    Reinheit

    >95 % by reducing SDS-PAGE

    Endotoxin-Niveau

    Less than 0.5 EU/mg of protein as determined by LAL method

    Immunogen

    Human CD22
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    > 3 mg/mL

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
  • Target

    CD22 (Epratuzumab Biosimilar)

    Andere Bezeichnung

    Epratuzumab Biosimilar

    Substanzklasse

    Biosimilar
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