Rekombinanter Abciximab Biosimilar Antikörper

Produktnummer ABIN7795100

Dieser Maus Monoklonal Antikörper detektiert spezifisch Abciximab Biosimilar in FACS und in vivo. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter Abciximab Biosimilar Antikörper (ABIN7795100)

Target: Abciximab Biosimilar

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Applikation: Flow Cytometry (FACS), In vivo Studies (in vivo)

Güteklasse: Research Grade

Produktdetails

Expressionssystem: Mammalian cells

Verwendungszweck: Abciximab Biosimilar, Glycoprotein IIb/IIIa Receptor Monoclonal Antibody

Produktmerkmale: Abciximab Biosimilar uses the same protein sequences as the therapeutic antibody abciximab. Abciximab, a glycoprotein IIb/IIIa receptor antagonist, is a platelet aggregation inhibitor mainly used during and after coronary artery procedures like angioplasty to prevent platelets from sticking together and causing thrombus (blood clot) formation within the coronary artery. It is a glycoprotein IIb/IIIa inhibitor. While abciximab has a short plasma half-life, due to its strong affinity for its receptor on the platelets, it may occupy some receptors for weeks. In practice, platelet aggregation gradually returns to normal about 96 to 120 hours after discontinuation of the drug. Abciximab is made from the Fab fragments of an immunoglobulin that targets the glycoprotein IIb/IIIa receptor on the platelet membrane.

Aufreinigung: Protein A or G affinity column

Reinheit: >95 % by reducing SDS-PAGE

Endotoxin-Niveau: < 1 EU per 1 mg of the protein by the LAL method

Immunogen: Human Glycoprotein IIb/IIIa Receptor

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: > 3 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Antigendetails

Target: Abciximab Biosimilar

Substanzklasse: Biosimilar