Rekombinanter IL-6R (Tocilizumab Biosimilar) Antikörper

Produktnummer ABIN7795095

Der Humanized Monoklonal Anti-IL-6R (Tocilizumab Biosimilar) Antikörper wurde für FACS und in vivo validiert. Er ist geeignet, IL-6R (Tocilizumab Biosimilar) in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter IL-6R (Tocilizumab Biosimilar) Antikörper (ABIN7795095)

Target: IL-6R (Tocilizumab Biosimilar)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Humanized

Klonalität: Monoklonal

Konjugat: Dieser IL-6R (Tocilizumab Biosimilar) Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), In vivo Studies (in vivo)

Güteklasse: Research Grade

Produktdetails anti-IL-6R (Tocilizumab Biosimilar) Antikörper

Expressionssystem: Mammalian cells

Verwendungszweck: Tocilizumab Biosimilar, Human IL-6R Monoclonal Antibody

Produktmerkmale: What is tocilizumab biosimilar research grade? Tocilizumab biosimilar uses the same protein sequences as the therapeutic antibody tocilizumab. Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. Interleukin 6 (IL-6) is a pro-inflammatory cytokine produced by cells including T-cells, B-cells, lymphocytes, monocytes, fibroblasts. IL-6 rapidly induces C-reactive protein, serum amyloid A, fibrinogen, haptoglobin, and α-1-antichymotrypsin while inhibiting production of fibronectin, albumin, and transferrin. IL-6 also induces antibody production, induces cytotoxic T-cell differentiation, and inhibits regulatory T-cell differentiation. Tocilizumab binds soluble and membrane bound IL-6 receptors, preventing IL-6 mediated inflammation.

Aufreinigung: Protein A or G affinity column

Reinheit: >95 % by reducing SDS-PAGE

Endotoxin-Niveau: < 1 EU per 1 mg of the protein by the LAL method

Immunogen: Human IL-6R

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: > 3 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Details zu IL-6R (Tocilizumab Biosimilar)

Target: IL-6R (Tocilizumab Biosimilar)

Andere Bezeichnung: Tocilizumab Biosimilar

Substanzklasse: Biosimilar