Influenza Virus Nucleoprotein Antikörper (Influenza A Virus)

Produktnummer ABIN7795018

Der Maus Monoklonal anti-Influenza Virus Nucleoprotein Antikörper (Klon IA-902) (ABIN7795018) detektiert spezifisch Influenza Virus Nucleoprotein in ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Influenza A Virus.

Kurzübersicht für Influenza Virus Nucleoprotein Antikörper (Influenza A Virus) (ABIN7795018)

Target: Influenza Virus Nucleoprotein (IV NP)

Reaktivität: Influenza A Virus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Klon: IA-902

Produktdetails

Verwendungszweck: Anti-Influenza A, Nucleocapsid

Spezifität: Anti-Influenza A, Nucleoprotein (Clone IA-902) is specific for the Influenza A nucleocapsid. Background There are four types of Influenza (flu) viruses type A, B, C, and D. Influenza A and B viruses are routinely spread in people and other mammals, while also known for seasonal flu epidemics each year. Influenza A is the genus Alphainfluenzavirus of the virus family Orthomyxoviridae. Influenza A is classified into two main protein subtypes, hemagglutinin (HA) and neuraminidase (NA), located on the surface of the virus. Breaking down the proteins further, there are 18 hemagglutinin subtypes and 11 different neuraminidase subtypes1. Influenza A can be even further classified into specific clades (also known as groups) and sub-clades (also known as sub-groups) based on similarity of their HA/NA gene sequences1. The Nucleocapsid protein or nucleoprotein (NP) of the influenza virus A negative-strand RNA?s primary function is to encapsulate the virus genome for the purpose of RNA transcription, replication and packaging2. Specifically, NP is the most abundant viral protein in infected cells2, therefore the NP can be and has been used for anti-influenza drug development3. The NP of influenza A and B viruses share up to 38 % of their amino acid sequence, indicating region functionality differences at the amino acid level4.

Aufreinigung: This monoclonal antibody is purified from ascites fluid or culture medium by protein A chromatography or sequential differential precipitations.

Reinheit: >90 % monomer by analytical SEC and SDS-Page

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA Recommended starting range 1:20-1:200 IF Recommended starting range 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/mL

Buffer: This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1 % sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: This product contains no stabilizing proteins and should be stored at 2-8°C until ready to use.

Antigendetails

Target: Influenza Virus Nucleoprotein (IV NP)

Andere Bezeichnung: Influenza A Nucleocapsid

Substanzklasse: Influenza Protein

Hintergrund: Common flu NP, Influenza A virus NP, NP, Nucleocapsid protein, Nucleoprotein, Protein N, Seasonal Influenza A (H1N1) Nucleocapsid Protein,