Anti-Influenza A, Nucleocapsid (Clone 703) specifically targets an epitope on the Influenza A Nucleocapsid Protein Antigen Distribution The nucleocapsid protein is expressed in the internal nucleocapsid of Influenza A Background There are four types of Influenza (flu) viruses type A, B, C, and D. Influenza A and B viruses are routinely spread in people and other mammals, while also known for seasonal flu epidemics each year. Influenza A is the genus Alphainfluenzavirus of the virus family Orthomyxoviridae. Influenza A is classified into two main protein subtypes, hemagglutinin (HA) and neuraminidase (NA), located on the surface of the virus. Breaking down the proteins further, there are 18 hemagglutinin subtypes and 11 different neuraminidase subtypes1. Influenza A can be even further classified into specific clades (also known as groups) and sub-clades (also known as sub-groups) based on similarity of their HA/NA gene sequences1. The Nucleocapsid protein or nucleoprotein (NP) of the influenza virus A negative-strand RNA?s primary function is to encapsulate the virus genome for the purpose of RNA transcription, replication and packaging2. Specifically, NP is the most abundant viral protein in infected cells2, therefore the NP can be and has been used for anti-influenza drug development3 The NP of influenza A and B viruses share up to 38 % of their amino acid sequence, indicating region functionality differences at the amino acid level4
IV NP
Reaktivität: Influenza A Virus H1N1, Influenza A Virus H5N1
IF
Wirt: Maus
Monoclonal
AA5H
unconjugated
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0.5 μg/mL
Buffer
This Biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1 % BSA and 0.09 % sodium azide as a preservative.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
Target
Influenza Virus Nucleoprotein (IV NP)
Andere Bezeichnung
Influenza A Nucleocapsid
Substanzklasse
Influenza Protein
Hintergrund
Common flu NP, Influenza A virus NP, NP, Nucleocapsid protein, Nucleoprotein, Protein N, Seasonal Influenza A (H1N1) Nucleocapsid Protein,