SARS-CoV-2 Spike Antikörper

Produktnummer ABIN7794949

Dieser Anti-SARS-CoV-2 Spike Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von SARS-CoV-2 Spike in . Geeignet für SARS Coronavirus-2 (SARS-CoV-2).

Kurzübersicht für SARS-CoV-2 Spike Antikörper (ABIN7794949)

Target: SARS-CoV-2 Spike

Reaktivität: SARS Coronavirus-2 (SARS-CoV-2)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SARS-CoV-2 Spike Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Klon: 2143

Produktdetails anti-SARS-CoV-2 Spike Antikörper

Verwendungszweck: Anti-SARS-CoV-2 Spike (Clone: 2143) Purified No Carrier Protein

Spezifität: Anti-SARS-CoV-2 Spike, clone 2143, specifically targets an epitope on the SARS-CoV-2 full length Spike protein (not specific to RBD or NTD). Antigen Distribution The spike is expressed on the surface of SARS-CoV-2. Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), is an enveloped, single-stranded, positive-sense RNA virus that belongs to the Coronaviridae family 1. The SARS-CoV-2 genome, which shares 79.6 % identity with SARS-CoV, encodes four essential structural proteins the spike (S), envelope (E), membrane (M), and nucleocapsid protein (N) 2. The S protein is a transmembrane, homotrimeric, class I fusion glycoprotein that mediates viral attachment, fusion, and entry into host cells 3. Each ~180 kDa monomer contains two functional subunits, S1 (~700 a.a) and S2 (~600 a.a), that mediate viral attachment and membrane fusion, respectively. S1 contains two major domains, the N-terminal (NTD) and C-terminal domains (CTD). The CTD contains the receptor-binding domain (RBD), which binds to the angiotensin-converting enzyme 2 (ACE2) receptor on host cells 3-5.

Aufreinigung: Recombinant antibodies are manufactured in an animal free facility using only in vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.

Reinheit: >=90 % monomer by analytical SEC and SDS-Page

Isotyp: IgG1

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/mL

Buffer: This recombinant monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: This antibody may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at <= -70°C.Avoid Repeated Freeze Thaw Cycles.

Details zu SARS-CoV-2 Spike

Target: SARS-CoV-2 Spike

Substanzklasse: Viral Protein

Hintergrund: COV2-2143, SARS-CoV-2 Spike Antibody,