Glutamate Dehydrogenase (GDH) Antikörper

Produktnummer ABIN7794693

Der Maus-Monoklonal Anti-Glutamate Dehydrogenase-Antikörper wurde für ELISA validiert. Er ist geeignet zum Nachweis von Glutamate Dehydrogenase in Proben aus Clostridium difficile. }

Kurzübersicht für Glutamate Dehydrogenase (GDH) Antikörper (ABIN7794693)

Target: Glutamate Dehydrogenase (GDH)

Reaktivität: Clostridium difficile

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: ELISA

Klon: CDIF-6581

Produktdetails

Verwendungszweck: Anti-Clostridium difficile, GDH (CDIF-6581)

Aufreinigung: This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations.

Reinheit: >=90 %

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/mL

Buffer: Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1 % sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: This purified antibody is stable when stored at 2-8°C. Do not freeze.

Antigendetails

Target: Glutamate Dehydrogenase (GDH)

Andere Bezeichnung: GDH

Hintergrund: GDH, glutamate dehydrogenase,?C. diff, C. difficile,Background: Clostridium difficile, often referred to as C. diff, is an anaerobic, Gram-positive bacterium that can cause a range of gastrointestinal issues in humans. Infections with C. difficile are primarily associated with healthcare settings such as hospitals and long-term care facilities where patients come into contact with infected individuals or contaminated surfaces1. C. diff infections (CDIs) typically occur following the disruption of the normal gut microbiota, often due to antibiotics, which allow the bacteria to proliferate and produce toxins2. Glutamate dehydrogenase (GDH) is an enzyme produced by C. difficile which is responsible for conversion of glutamate to alpha-ketoglutarate. GDH detection in the stool is often used as a rapid screening tool to suggest possible presence of C. diff. Further testing for the bacterial toxins is typically performed upon a positive GDH test.