Integrin Alpha3, Beta1 (AA 976-1025) Antikörper (HRP)

Produktnummer ABIN737040

Produktdetails

Target: Integrin Alpha3, Beta1

Bindungsspezifität: AA 976-1025

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: Mixed KLH conjugated synthetic peptide derived from human Integrin Alpha 3(976-1025/1051) + Beta 1(35-47/798)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Integrin Alpha3, Beta1

Andere Bezeichnung: Integrin Alpha 3 + Beta 1

Hintergrund:

Synonyms: Integrin Alpha 3 / Beta 1, Integrin VLA 4 beta subunit, Alpha 3 subunit of VLA 3 receptor, CD29, CD49C, Fibronectin receptor, Fibronectin receptor beta subunit, Galactoprotein B3, GAPB3, VL3A, VLA 3 alpha chain, VLA3a.

Background: alpha3beta1 integrin is a laminin receptor with apparently diverse functions. In epithelial cells it acts as a receptor for the basement membrane, whereas in neuronal and possibly tumor cells it mediates migration. Interactions of alpha3beta1 integrin with tetraspanin proteins may provide clues to how it transduces signals that affect cell behavior.

Gen-ID: 3675, 3688

UniProt: P26006, P05556