Prostaglandin E Synthase Antikörper (PE-Cy5)

Produktnummer ABIN735800

Der Kaninchen Polyklonal Anti-Prostaglandin E Synthase-Antikörper wurde für WB validiert. Er ist geeignet, Prostaglandin E Synthase in Proben von Human, Ratte, Maus und Meerschweinchen zu detektieren.

Kurzübersicht für Prostaglandin E Synthase Antikörper (PE-Cy5) (ABIN735800)

Target: Prostaglandin E Synthase (PTGES)

Reaktivität: Human, Ratte, Maus, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prostaglandin E Synthase Antikörper ist konjugiert mit PE-Cy5

Applikation: Western Blotting (WB)

Produktdetails anti-Prostaglandin E Synthase Antikörper (PE-Cy5)

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Pig,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PTGEs

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Prostaglandin E Synthase

Target: Prostaglandin E Synthase (PTGES)

Andere Bezeichnung: PTGEs

Hintergrund:

Synonyms: PGES, MPGES, PIG12, PP102, PP1294, MGST-IV, MGST1L1, TP53I12, mPGES-1, MGST1-L1, Prostaglandin E synthase, Microsomal glutathione S-transferase 1-like 1, Microsomal prostaglandin E synthase 1, p53-induced gene 12 protein, PTGES, MPGES1

Background: Prostaglandin E synthase catalyses conversion of COX derived PGH2 to PGE2. It is a member of the MAPEG family. It may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain during inflammatory responses.The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.

Molekulargewicht: 17kDa

Gen-ID: 9536

UniProt: O14684