Ldha/Ldh Antikörper

Produktnummer ABIN734768

Der Kaninchen Polyklonal anti-Ldha/Ldh Antikörper wird verwendet zum Nachweis von Ldha/Ldh in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IF (p) und IHC (p).

Kurzübersicht für Ldha/Ldh Antikörper (ABIN734768)

Target: Ldha/Ldh

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LDH

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Antigendetails

Target: Ldha/Ldh

Hintergrund:

Synonyms: Lactate Dehydrogenase, Lactate Dehydrogenase Isoenzyme V, Lactate Dehydrogenase isozyme H4, L lactate dehydrogenase A chain, Lactate dehydrogenase A, Lactate dehydrogenase A chain, LDH A, LDH heart subunit, LDH M, LDHM, LDH muscle subunit, LDH1, LDHA, PIG 19, PIG19, Proliferation inducing gene 19 protein, TRG 5, TRG5, LDHA_HUMAN.

Background: The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.Lactate dehydrogenase is an enzyme present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. Isoforms of the enzyme include LDH 1 (4H) in the heart, LDH 2 (3H1M) in the reticuloendothelial system, LDH 3 (2H2M) in the lungs, LDH 4 (1H3M) in the kidneys and LDH 5 (4M) in the liver and striated muscle. The M and H subunits are encoded by two different genes.

Gen-ID: 3939