CD163 Antikörper (FineTest®700)

Produktnummer ABIN7674900

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD163 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD163 Antikörper (FineTest®700) (ABIN7674900)

Target: CD163

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD163 Antikörper ist konjugiert mit FineTest®700

Applikation: Flow Cytometry (FACS)

Klon: GHI-61

Produktdetails anti-CD163 Antikörper (FineTest®700)

Verwendungszweck: FineTest®700 Anti-Human CD163 Antibody

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu CD163

Target: CD163

Andere Bezeichnung: CD163

Hintergrund:

Synonyms: ED2(rat)Hemoglobin/Haptoglobin Complex ReceptorM130RM3/1macrophage-associated antigenp155|GHI/61

Background: CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.

Molekulargewicht: 0

Gen-ID: 9332

UniProt: Q86VB7