UBASH3A Antikörper
Kurzübersicht für UBASH3A Antikörper (ABIN7674580)
Target
Alle UBASH3A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- UBASH3A-Specific antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- ubiquitin associated and SH3 domain containing, A
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:200-1:2000, IF: 1:10-1:100,IP: 1:200-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))
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Andere Bezeichnung
- UBASH3A
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Hintergrund
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Synonyms: Ubiquitin-associated and SH3 domain-containing protein A|Cbl-interacting protein 4 (CLIP4)|Suppressor of T-cell receptor signaling 2 (STS-2)|T-cell ubiquitin ligand 1 (TULA-1)|UBASH3A|STS2
Background: UBASH3A gene encodes ubiquitin-associated and SH3 domain-containing protein A(UBASH3A) also known as T-cell ubiquitin ligand 1(TULA1) which is one of two family members belonging to the T-cell ubiquitin ligand(TULA) family. UBASH3A gene expression is limited to only a few tissues, with its highest expression in spleen, peripheral blood leukocytes, and bone marrow. UBASH3A protein is associated with c-Cbl and ubiquitylated proteins and has been implicated in the regulation of signaling mediated by protein-tyrosine kinases oth family members can negatively regulate T-cell signaling. UBASH3A can facilitate growth factor withdrawal-induced apoptosis in T cells via its interaction with apoptosis-inducing factor(AIF). This antibody is UBASH3A-specific.
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Molekulargewicht
- 69 kDa
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Gen-ID
- 53347
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UniProt
- P57075
Target
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