Integrin beta 7 Antikörper (PerCP-Cy5.5)

Produktnummer ABIN7674298

Dieses Anti-Integrin beta 7-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von Integrin beta 7 in FACS. Geeignet für Human und Maus.

Kurzübersicht für Integrin beta 7 Antikörper (PerCP-Cy5.5) (ABIN7674298)

Target: Integrin beta 7 (ITGB7)

Reaktivität: Human, Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Integrin beta 7 Antikörper ist konjugiert mit PerCP-Cy5.5

Applikation: Flow Cytometry (FACS)

Klon: FIB21

Produktdetails anti-Integrin beta 7 Antikörper (PerCP-Cy5.5)

Verwendungszweck: PerCP-Cy5.5 Anti-Human/Mouse Integrin β7 Antibody

Aufreinigung: 0

Reinheit: 0

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu Integrin beta 7

Target: Integrin beta 7 (ITGB7)

Andere Bezeichnung: Integrin beta7

Hintergrund:

Synonyms: β7 Integrin|integrin βp|ITGB7

Background: Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7,αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.

Molekulargewicht: 0

Gen-ID: 3695

UniProt: P26010, P26011

Pathways: Integrin Complex