2B4 Antikörper (PE-Cy5)

Produktnummer ABIN7673809

Dieses Anti-2B4-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von 2B4 in FACS. Geeignet für Human.

Kurzübersicht für 2B4 Antikörper (PE-Cy5) (ABIN7673809)

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser 2B4 Antikörper ist konjugiert mit PE-Cy5

Applikation: Flow Cytometry (FACS)

Klon: C1-7

Produktdetails anti-2B4 Antikörper (PE-Cy5)

Verwendungszweck: PE-Cy5 Anti-Human CD244 Antibody

Aufreinigung: 0

Reinheit: 0

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu 2B4

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Andere Bezeichnung: CD244

Hintergrund:

Synonyms: 2B4|SLAMF4

Background: CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including most CD8+ T cells and γ/δ T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression.

Molekulargewicht: 0

Gen-ID: 51744

UniProt: Q9BZW8