IFNGR1 Antikörper (PE)

Produktnummer ABIN7673684

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch IFNGR1 in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für IFNGR1 Antikörper (PE) (ABIN7673684)

Target: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IFNGR1 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: GR-20

Produktdetails anti-IFNGR1 Antikörper (PE)

Verwendungszweck: PE Anti-Mouse CD119 Antibody

Aufreinigung: 0

Reinheit: 0

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu IFNGR1

Target: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Andere Bezeichnung: CD119

Hintergrund:

Synonyms: CD119|IFN-gamma-R-alpha|IFN-gamma-R1|Ifngr1|Interferon gamma receptor 1

Background: CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

Molekulargewicht: 0

Gen-ID: 15979

UniProt: P15261

Pathways: Interferon-gamma Pathway