MTDH Antikörper

Produktnummer ABIN7673471

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MTDH in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für MTDH Antikörper (ABIN7673471)

Target: MTDH (Metadherin (MTDH))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MTDH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-MTDH Antikörper

Verwendungszweck: MTDH-Specific antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: metadherin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu MTDH

Target: MTDH (Metadherin (MTDH))

Andere Bezeichnung: MTDH

Hintergrund:

Synonyms: Protein LYRIC|3D3/LYRIC|Astrocyte elevated gene-1 protein (AEG-1)|Lysine-rich CEACAM1 co-isolated protein|Metadherin|Metastasis adhesion protein|MTDH|AEG1|LYRIC

Background: MTDH, also known as AEG-1, is a single-pass transmembrane protein with its gene located at chromosome 8q22, the abnormalities of which have been identified in several tumor types. MTDH is overexpressed in a number of malignancies, such as breast cancer, malignant glioma, and neuroblastoma, and its overexpression is associated with poor clinical outcome. MTDH plays an important role in the regulation of carcinogenesis and tumor progression. This antibody got two bands about 70 kDa and 80 kDa in western blotting, possibly due to posttranslational modification. This antibody is specific to AEG-1/MTDH.

Molekulargewicht: 64 kDa

Gen-ID: 92140

UniProt: Q86UE4

Pathways: Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization