Non-Syndromic Hearing Impairment Protein 5 (GSDME) Antikörper

Produktnummer ABIN7673342

Dieses Maus Monoklonal-Antikörper erkennt spezifisch in ELISA und WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Non-Syndromic Hearing Impairment Protein 5 (GSDME) Antikörper (ABIN7673342)

Target: Non-Syndromic Hearing Impairment Protein 5 (GSDME)

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Klon: 8A1

Produktdetails

Verwendungszweck: GSDME antibody

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen: deafness, autosomal dominant 5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Antigendetails

Target: Non-Syndromic Hearing Impairment Protein 5 (GSDME)

Andere Bezeichnung: GSDME

Hintergrund:

Synonyms: Gasdermin-E|Inversely correlated with estrogen receptor expression 1 (ICERE-1)|Non-syndromic hearing impairment protein 5|Gasdermin-E, N-terminal (GSDME-NT)|Gasdermin-E, C-terminal (GSDME-CT)|GSDME|DFNA5|ICERE1

Background: Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.

Molekulargewicht: 50-55 kDa

Gen-ID: 1687

UniProt: O60443