SIGLEC9 Antikörper (APC)

Produktnummer ABIN7672709

Dieses Maus Monoklonal-Antikörper erkennt spezifisch SIGLEC9 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SIGLEC9 Antikörper (APC) (ABIN7672709)

Target: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SIGLEC9 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: K8

Produktdetails anti-SIGLEC9 Antikörper (APC)

Verwendungszweck: APC Anti-Human CD329 Antibody

Aufreinigung: 0

Reinheit: 0

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu SIGLEC9

Target: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Andere Bezeichnung: CD329

Hintergrund:

Synonyms: Siglec-9|Sialic acid-binding Ig-like lectin-9,

Background: Siglecs are cell surface receptors belonging to the immunoglobulin superfamily that recognize sugar antigens. The extracellular domain of siglec-9 contains an IgV region, which binds sialic acid, followed by two IgC regions. Siglec 9 and siglec 6-8,10-12 are CD33 (siglec 3) like siglecs, which have two ITIMs in the cytoplasmic tails, suggesting their functional involvement in signal transduction. It is highly expressed on neutrophils and monocytes, and at lower levels on the subpopulations of T and B lymphocytes and NK cells. Siglec-9 plays a role in negative regulation of T cell activation, and it also affects neutrophil apoptosis.

Molekulargewicht: 0

Gen-ID: 27180

UniProt: Q9Y336