Fc gamma RII (CD32) Antikörper (APC)

Produktnummer ABIN7672707

Der Maus Monoklonal Anti--Antikörper wurde für FACS validiert. Er ist geeignet, in Proben von Human zu detektieren.

Kurzübersicht für Fc gamma RII (CD32) Antikörper (APC) (ABIN7672707)

Target: Fc gamma RII (CD32)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: APC

Applikation: Flow Cytometry (FACS)

Klon: IV-3

Produktdetails

Verwendungszweck: APC Anti-Human CD32 Antibody

Aufreinigung: 0

Reinheit: 0

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Antigendetails

Target: Fc gamma RII (CD32)

Andere Bezeichnung: CD32

Hintergrund:

Synonyms: IGFR2|CD32|CDw32|FCG2|FCGR2B|Fc-gamma RII-b|Fc-gamma-RIIb|FcRII-b|IgG Fc receptor II-b|Low affinity immunoglobulin gamma Fc region receptor II-b

Background: CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

Molekulargewicht: 0

Gen-ID: 2212

UniProt: P31994