SNCA Antikörper

Produktnummer ABIN7670751

Der Ratte Monoklonal Anti-SNCA-Antikörper wurde für ELISA (Detection) validiert. Er ist geeignet, SNCA in Proben von Human zu detektieren.

Kurzübersicht für SNCA Antikörper (ABIN7670751)

Target: SNCA (Synuclein, alpha (SNCA))

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser SNCA Antikörper ist unkonjugiert

Applikation: ELISA (Detection)

Klon: 4H12

Produktdetails anti-SNCA Antikörper

Verwendungszweck: alpha-Synuclein/SNCA Monoclonal Antibody(Detector)

Aufreinigung: Protein A/G Purification

Immunogen: Recombinant Human alpha-Synuclein/SNCA protein expressed by E.coli

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu SNCA

Target: SNCA (Synuclein, alpha (SNCA))

Andere Bezeichnung: alpha-Synuclein/SNCA

Hintergrund: SNC-A,aSYN,PD1,NACP,PARK1,PARK4,Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.

UniProt: P37840

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity