PPY Antikörper

Produktnummer ABIN7670710

Dieses Anti-PPY-Antikörper ist ein Ratte Polyklonal-Antikörper zur Detektion von PPY in ELISA. Geeignet für Human.

Kurzübersicht für PPY Antikörper (ABIN7670710)

Target: PPY (Pancreatic Polypeptide (PPY))

Reaktivität: Human

Wirt: Ratte

Klonalität: Polyklonal

Konjugat: Dieser PPY Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-PPY Antikörper

Verwendungszweck: Pancreatic polypeptide/PPY Polyclonal Antibody

Aufreinigung: Antigen Affinity Purification

Immunogen: Recombinant Human Pancreatic polypeptide/PPY protein expressed by E.coli

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu PPY

Target: PPY (Pancreatic Polypeptide (PPY))

Andere Bezeichnung: Pancreatic polypeptide/PPY

Hintergrund: Pancreatic poLypeptide prohormone,PH,Pancreatic poLypeptide Y,Pancreatic poLypeptide,Pancreatic icosapeptide,PPY,PNP,Pancreatic polypeptide (PP),36-amino acid peptide,may function as an important feedback inhibitor of pancreatic secretion after a meal. It arises from both islet and acinar cells of the pancreas. Release of PP by a meal,primarily protein,occurs in a biphasic manner. PP is a negative regulator of energy homeostasis that suppresses food intake and lowers body weight. Similar to other gastrointestinal-derived peptides,PP also modulates gastrointestinal motility and may be involved in the regulation of anxiety. PP,a robust anorexigenic hormone,effectively modulates food intake and energy homeostasis,thus potentially aiding anti-obesity therapeutics. PP is produced in pancreatic islets of Langerhans and released into the circulation after ingestion of a meal. Peripherally administered PP suppresses food intake and gastric emptying. On the other hand,central administration of PP elicits food intake and gastric emptying.

UniProt: P01298

Pathways: Feeding Behaviour