IL-22 Antikörper

Produktnummer ABIN7670665

Dieses Anti-IL-22-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von IL-22 in ELISA (Detection). Geeignet für Human.

Kurzübersicht für IL-22 Antikörper (ABIN7670665)

Target: IL-22 (IL22) (Interleukin 22 (IL22))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-22 Antikörper ist unkonjugiert

Applikation: ELISA (Detection)

Klon: 4E6

Produktdetails anti-IL-22 Antikörper

Verwendungszweck: IL-22 Monoclonal Antibody(Detector)

Aufreinigung: Protein A/G Purification

Immunogen: Recombinant Human IL-22 protein expressed by Mammalian

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu IL-22

Target: IL-22 (IL22) (Interleukin 22 (IL22))

Andere Bezeichnung: IL-22

Hintergrund: Cytokine Zcyto18,IL-10-reLated T-ceLL-derived inducibLe factor,IL22,IL-22,IL-D110,IL-TIF,ILTIFIL-10-reLated T-ceLL-derived-inducibLe factor,IL-TIFMGC79382,interLeukin 22,interLeukin-22,MGC79384,TIFa,TIFIL-23,zcyto18,Interleukin-22 (Il-22),also known as Il-10-related T cell-derived inducible factor (Il-TIF) was initially identified as a gene induced by Il-9 in mouse T cells and mast cells. Mouse Il-22 cDNA encodes a 179 amino acid (aa) residue protein with a putative 33 aa signal peptide that is cleaved to generate a 147 aa mature protein that shares approximately 79 % and 22 % aa sequence identity with human Il-22 and Il-10,respectively. The mouse Il-22 gene is localized to chromosome 10. Although it exists as a single copy gene in many mouse strains,the Il-22 gene is duplicated in some mouse strains including C57B1/6,FVB and 129. The two mouse genes designated Il-TIF alpha and Il-TIF beta,share greater than 98 % sequence homology in their coding region. Il-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. Il-22 is produced by normal mouse T cells upon Con A activation. Mouse Il-22 expression is also induced in various organs upon lipopolysaccharide injection,suggesting that Il-22 may be involved in inflammatory responses. The functional Il-22 receptor complex consists of two receptor subunits,Il-22 R (previously an orphan receptor named CRF2-9) and Il-10 R beta (previously known as CRF2-4),belonging to the class II cytokine receptor family.

UniProt: Q9GZX6