ICAM1 Antikörper

Produktnummer ABIN7670647

Dieses Anti-ICAM1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ICAM1 in ELISA (Capture). Geeignet für Ratte.

Kurzübersicht für ICAM1 Antikörper (ABIN7670647)

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ICAM1 Antikörper ist unkonjugiert

Applikation: ELISA (Capture)

Klon: 2F7

Produktdetails anti-ICAM1 Antikörper

Verwendungszweck: ICAM-1/CD54 Monoclonal Antibody(Capture)

Aufreinigung: Protein A/G Purification

Immunogen: Recombinant Rat ICAM-1/CD54 Protein expressed by Mammalian

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA Capture 2-8 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Andere Bezeichnung: ICAM-1/CD54

Hintergrund: InterceLLuLar adhesion moLecuLe 1,ICAM-1,CD54,Icam1,Icam-1,ICAM-1 (intercellular adhesion molecule-1),also known as CD54,is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated lFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin,Fibrinogen,Hyaluronan,rhinoviruses,and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease,type 2 diabetes,organ transplant dysfunction,oxidant stress,increased abdominal fat mass,hypertension,liver disease,certain malignancies,and cerebral malaria.

UniProt: Q00238

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling