Dieser Anti-TCR V Alpha24-J Alpha18-Antikörper ist ein Maus-Monoklonal-Antikörper zum Nachweis von TCR V Alpha24-J Alpha18 in FACS. Geeignet für Human.
Reaktivität: Human, Non-Human Primate
FACS
Wirt: Maus
Monoclonal
6B11
PE
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
5 μL/tests
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant
Handhabung
Please protected from prolonged exposure to light and do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
This product can be stored at 2-8°C for 12 months.
Haltbarkeit
12 months
Target
TCR V Alpha24-J Alpha18
Andere Bezeichnung
TCR Valpha24-Jalpha18
Hintergrund
TCR Vα24-Jα18,TCR Vα24-JαQ,invariant NKT cell,iNKT,Encoded by the TCR Vα24-Jα18 germline configuration, Vα24-JαQ is expressed on a subset of NKT cells, namely invariant NKT (iNKT). Vα24-JαQ TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production. iNKT cells have been implicated in immune regulation, tumor surveillance, and host response to pathogens. While iNKT cells occur at low frequency in the blood, assorted chemokines contribute to their tissue homing potential.