Integrin beta 7 Antikörper (PE)
Kurzübersicht für Integrin beta 7 Antikörper (PE) (ABIN7670235)
Target
Alle Integrin beta 7 (ITGB7) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- PE Anti-Human Integrin β7 Antibody[FIB504]
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Isotyp
- IgG2a, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 5 μL/tests
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Buffer
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
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Handhabung
- Please protected from prolonged exposure to light and do not freeze.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- This product can be stored at 2-8°C for 12 months.
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Haltbarkeit
- 12 months
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- Integrin beta 7 (ITGB7)
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Andere Bezeichnung
- Integrin beta7
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Hintergrund
- CEACAM1a,Bgp,Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7,αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.
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UniProt
- P31809
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Pathways
- Integrin Complex
Target
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