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Integrin beta 7 Antikörper (PE)

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch Integrin beta 7 in FACS. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7670235

Kurzübersicht für Integrin beta 7 Antikörper (PE) (ABIN7670235)

Target

Alle Integrin beta 7 (ITGB7) Antikörper anzeigen
Integrin beta 7 (ITGB7)

Reaktivität

  • 77
  • 31
  • 1
  • 1
  • 1
Human

Wirt

  • 50
  • 20
  • 7
  • 4
  • 1
Ratte

Klonalität

  • 51
  • 29
  • 2
Monoklonal

Konjugat

  • 36
  • 8
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Integrin beta 7 Antikörper ist konjugiert mit PE

Applikation

  • 40
  • 28
  • 21
  • 13
  • 13
  • 8
  • 8
  • 8
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

FIB504
  • Verwendungszweck

    PE Anti-Human Integrin β7 Antibody[FIB504]

    Immunogen

    E-AB-F09832D

    Isotyp

    IgG2a, kappa
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    5 μL/tests

    Buffer

    Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

    Handhabung

    Please protected from prolonged exposure to light and do not freeze.

    Lagerung

    4 °C

    Informationen zur Lagerung

    This product can be stored at 2-8°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    Integrin beta 7 (ITGB7)

    Andere Bezeichnung

    Integrin beta7

    Hintergrund

    CEACAM1a,Bgp,Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7,αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.

    UniProt

    P31809

    Pathways

    Integrin Complex
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