Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
5 μL/tests
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
Handhabung
Please protected from prolonged exposure to light and do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
This product can be stored at 2-8°C for 12 months.
Haltbarkeit
12 months
Target
ITGA4
(Integrin alpha 4 (ITGA4))
Andere Bezeichnung
LPAM-1
Hintergrund
α4β7 Integrin,CD49d/β7,LPAM-1,ITGA4,ITGB7,DATK32 antibody is specific for a combinatorial determinate of integrin α4β7complex. Integrin α4β7 is composed of a 150 kD (α4 or CD49d) and a 130 kD (β7) heterodimer, also known as CD49d/β7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors). Integrin α4β7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues.