Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
5 μL/tests
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
Handhabung
Please protected from prolonged exposure to light and do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
This product can be stored at 2-8°C for 12 months.
Haltbarkeit
12 months
Target
CD8 alpha (CD8A)
(CD8a Molecule (CD8A))
Andere Bezeichnung
CD8a
Hintergrund
CD19 Molecule,CD19 Antigen,Differentiation Antigen CD19,B-Lymphocytes Surface Antigen B4,T-cell Surface Antigen Leu-12,CVID3,B4,B-lymphocyte Antigen CD19,CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.