CD8 Antikörper (PE,Cy5)

Produktnummer ABIN7670215

Der Maus Monoklonal Anti-CD8 Antikörper wurde für FACS validiert. Er ist geeignet, CD8 in Proben von Human zu detektieren.

Kurzübersicht für CD8 Antikörper (PE,Cy5) (ABIN7670215)

Target: CD8

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD8 Antikörper ist konjugiert mit PE,Cy5

Applikation: Flow Cytometry (FACS)

Klon: UCHT-4

Produktdetails anti-CD8 Antikörper (PE,Cy5)

Verwendungszweck: PE/Cyanine5 Anti-Human CD8 Antibody[UCHT-4]

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 5 μL/tests

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Handhabung: Please protected from prolonged exposure to light and do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: This product can be stored at 2-8°C for 12 months.

Haltbarkeit: 12 months

Details zu CD8

Target: CD8

Andere Bezeichnung: CD8

Hintergrund: T8,Leu2,CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck

UniProt: P01732